25 Most Painful Diseases You Wouldn’t Want to Have

#22 – Stone Man Syndrome

This disease is so painful that we wouldn’t even wish it to our worst nemesis. Stone Man Syndrome is formally known in the medicine as Fibrodysplasia Ossificans Progressive. The disease is extremely rare.

Stone Man Syndrome is caused by a rare genetic mutation that has to deal with the body’s repair mechanism. People with Stone Man Syndrome experience indescribable pains while all of their ligaments, tendons, and muscles turn into bone. Inevitably, such people become immobilized and die in extreme pain.